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Vasculitis
“Vasculitis” is a general term for a group of diseases that involve inflammation in blood vessels. Blood vessels of all sizes may be affected, from the largest vessel in the body (the aorta) to the smallest blood vessels in the skin (capillaries). The size of the blood vessel affected varies according to the specific type of vasculitis.
When a blood vessel is inflamed, it can narrow or close off. This limits or prevents blood from getting through the vessel. Rarely, the blood vessel will stretch and weaken, causing it to bulge. This bulge is known as an aneurysm. The disruption in blood flow from inflammation can damage the body's organs. Signs and symptoms depend on which organs have been damaged and the extent of the damage.
Typical symptoms of inflammation, such as fever and general aches and pains, are common among people who have vasculitis.
Wegener's Granulomatosis (WG) is closely associated with antineutrophil cytoplasmic autoantibodies (ANCA), particularly those directed to proteinase 3 (PR3). ANCAs directed to myeloperoxidase (MPO) are associated with microscopic polyangiitis (MPA) and Churg-Strauss syndrome. PR3-ANCA associated vasculitis differs from MPO-ANCA associated vasculitis particularly in the occurrence of granulomatous inflammation and more widespread disease in the former condition.
For more information, please select from the following list:
IMTEC-GBM-Antibodies
ELISA for the Quantitativ Determination of Anti-GBM-Antibodies (IgG) | 96 Tests.
ITC82070
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IMTEC-PR3-ANCA
ELISA for the Quantitativ Determination of Anti-Proteinase 3-Antibodies (IgG) | 96 Tests.
ITC82020
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IMTEC-MPO-ANCA
ELISA for the Quantitativ Determination of Anti-Myeloperoxidase-Antibodies (IgG) | 96 Tests.
ITC82030
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IMTEC-Vasculitis-LIA
Line Immuno Assay (LIA) for the Detection of Antibodies in autoimmune Vasculitis (PR3, MPO and GBM) | 24 Tests.
ITC82040
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Human
