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ProductsHumanAutoimmune DiagnosticsAntiphospholipid Syndrome / Gynecology
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  Antiphospholipid Syndrome / Gynecology

Antiphospholipid syndrome (APS) is an autoimmune disease characterized by a multitude of possible clinical, hematological and serological manifestations. These include venous and / or arterial thrombosis, (recurrent)miscarriages, premature births on the basis of (pre) eclampsia or of placental insufficiency.

In most patients with antiphospholipid - syndrome, certain so-called antiphospholipid antibodies (eg. lupus anticoagulant (LA), anti Cardiolipin antibodies, antibodies to ß2 Glycoprotein-I or antibodies to phosphatidylserine) can be detected.

Antiphospholipid antibodies probably induce thrombosis through theactivation of clotting and / or by impeding inhibiting clotting factors. Antiphospholipid antibodies (APA) occur in 90% of thrombosis patients and show increased frequency in genetically predisposed family members of the patients. Women represent 80% of cases.

APA are antibodies belonging to IgG and IgM, and, rarely, to the IgA isotype family, which are specific for clotting active phospholipids (Phosphatidylinositol, Phosphatidylserine, Phosphatidyletholamine and Cardiolipin). APAs do not bind directly to these phospholipids but rather to plasma proteins which are complexes with phospholipids. The plasma proteins include ß2-Glycoprotein I.


For more information, please select from the following list:

IMTEC-Cardiolipin-Antibodies Screen

ELISA for the Quantitative Determination of Anti-Cardiolipin-Antibodies (Ig(GAM)) | 96 Tests.

ITC59076
  IMTEC-Cardiolipin-Antibodies Combi

ELISA for the Quantitative Determination of Anti-Cardiolipin-Antibodies (IgG und IgM) | 96 Tests.

ITC59082
  IMTEC-Cardiolipin-Antibodies IgG

ELISA for the Quantitative Determination of Anti-Cardiolipin-Antibodies (Ig(GAM)) | 96 Tests.

ITC59071
  IMTEC-Cardiolipin-Antibodies IgM

ELISA for the Quantitative Determination of Anti-Cardiolipin-Antibodies (Ig(GAM)) | 96 Tests.

ITC59081


IMTEC-Cardiolipin-Antibodies IgA

ELISA for the Quantitative Determination of Anti-Cardiolipin-Antibodies (Ig(GAM)) | 96 Testssl.

ITC59075
  IMTEC-Phosphatidylserine-Antibodies Screen

ELISA for the Quantitative Determination of Anti-Phosphatidylserine-Antibodies (Ig(GAM)) | 96 Tests.

ITC59027
  IMTEC-Phosphatidylserine-Antibodies Combi

ELISA for the Quantitative Determination of Anti-Phosphatidylserine-Antibodies (IgG und IgM) | 96 Tests.

ITC59022
  IMTEC-Phosphatidylserine-Antibodies IgG

ELISA for the Quantitative Determination of Anti-Phosphatidylserine-Antibodies (IgG) | 96 Tests.

ITC59011


IMTEC-Phosphatidylserine-Antibodies IgM

ELISA for the Quantitative Determination of Anti-Phosphatidylserine-Antibodies (IgM) | 96 Tests.

ITC59021
  IMTEC-Phosphatidylserine-Antibodies IgA

ELISA for the Quantitative Determination of Anti-Phosphatidylserine-Antibodies (IgA) | 96 Tests.

ITC59025
  IMTEC-Phosphatidylethanolamine- Antibodies Screen

ELISA for the Quantitative Determination of Anti-Phosphatidylethanolamine- Antibodies (Ig(GAM)) | 96 Tests.

ITC59400
  IMTEC-ß2-Glycoprotein I-Antibodies Screen

ELISA for the Quantitative Determination of Anti-?2-Glycoprotein I-Antibodies (Ig(GAM)) | 96 Tests.

ITC59050


IMTEC-ß2-Glycoprotein I-Antibodies IgG

ELISA for the Quantitative Determination of Anti-?2-Glycoprotein I-Antibodies (IgG) | 96 Tests.

ITC59150
  IMTEC-ß2-Glycoprotein I-Antibodies IgM

ELISA for the Quantitative Determination of Anti-?2-Glycoprotein I-Antibodies (IgM) | 96 Tests.

ITC59250
  IMTEC-ß2-Glycoprotein I-Antibodies IgA

ELISA for the Quantitative Determination of Anti-?2-Glycoprotein I-Antibodies (IgA) | 96 Tests.

ITC59350
  IMTEC-Prothrombin-Antibodies Screen

ELISA for the Quantitative Determination of Anti-Prothrombin-Antibodies (Ig(GAM)) | 96 Tests.

ITC59450


IMTEC-Annexin V-Antibodies Screen

ELISA for the Quantitative Determination of Anti-Annexin V-Antibodies (Ig(GAM)) | 96 Tests.

ITC59550
  IMTEC-oxLDL-Antibodies Ig(GM)

oxLDL | IgG/IgM.

ITC59500
  IMTEC-Spermatozoal-Antibodies Screen

Human sperm antigens IgG/IgA/IgM

ITC88010
   
 
 
 

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